hsc full form
Abstract ( hsc full form ) It is believed that the mammalian blood System is comprised of more than ten types of mature cells. It is built on one type of cell called hematopoietic stem cells (HSC). Within the system, only HSC that are capable of self-renewal as well as multi-potency. Multi-potency means the ability to differentiate into functional blood cells of all kinds. Self-renewal can give rise to HSC that are not differentiated. Because mature blood cells are typically short lived, HSC continuously provide more differentiated progenitors and are able to maintain the HSC size at a suitable level throughout their lives by precisely the balance between self-renewal and differentiation. Therefore, understanding the mechanism of self-renewal and differentiation HSC is an important problem. In this review, we concentrate on the hi-level structure of the hematopoietic system, what we currently know about microenvironmental and ...